An integrin-like protein in Candida albicans: Implications for pathogenesis

Margaret K. Hostetter

doi:10.1016/0966-842X(96)10036-6

An integrin-like protein in Candida albicans: Implications for pathogenesis

Margaret K. Hostetter

University of Minnesota Twin Cities

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.

Original language	English
Pages (from-to)	242-246
Number of pages	5
Journal	Trends in Microbiology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0966-842X(96)10036-6
State	Published - Jun 1996
Externally published	Yes

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10.1016/0966-842X(96)10036-6

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title = "An integrin-like protein in Candida albicans: Implications for pathogenesis",

abstract = "Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.",

author = "Hostetter, \{Margaret K.\}",

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T2 - Implications for pathogenesis

AU - Hostetter, Margaret K.

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N2 - Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.

AB - Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.

UR - https://www.scopus.com/pages/publications/0029894343

U2 - 10.1016/0966-842X(96)10036-6

DO - 10.1016/0966-842X(96)10036-6

M3 - Review article

C2 - 8795161

AN - SCOPUS:0029894343

SN - 0966-842X

VL - 4

SP - 242

EP - 246

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 6

ER -

An integrin-like protein in Candida albicans: Implications for pathogenesis

Abstract

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