Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Chris A. Rees; Andrea T. Cruz; Stephen B. Freedman; Prashant Mahajan; Neil G. Uspal; Pamela Okada; Paul L. Aronson; Amy D. Thompson; Paul T. Ishimine; Suzanne M. Schmidt; Nathan Kuppermann; Lise E. Nigrovic

doi:10.1093/jpids/piy126

Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Chris A. Rees
, Andrea T. Cruz
, Stephen B. Freedman
, Prashant Mahajan
, Neil G. Uspal
, Pamela Okada
, Paul L. Aronson
, Amy D. Thompson
, Paul T. Ishimine
, Suzanne M. Schmidt
, Nathan Kuppermann
, Lise E. Nigrovic

Harvard University
Baylor College of Medicine
University of Calgary
University of Michigan, Ann Arbor
Seattle Children's
University of Texas Southwestern Medical Center
Yale University
Alfred I. duPont Hospital for Children
Rady Children's Hospital
Northwestern University
University of California at Davis

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.

Original language	English
Pages (from-to)	559-562
Number of pages	4
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	8
Issue number	6
DOIs	https://doi.org/10.1093/jpids/piy126
State	Published - 1 Dec 2019
Externally published	Yes

Keywords

bacterial meningitis score
infants
sensitivity
specificity

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10.1093/jpids/piy126

Cite this

Rees, C. A., Cruz, A. T., Freedman, S. B., Mahajan, P., Uspal, N. G., Okada, P., Aronson, P. L., Thompson, A. D., Ishimine, P. T., Schmidt, S. M., Kuppermann, N., & Nigrovic, L. E. (2019). Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days. Journal of the Pediatric Infectious Diseases Society, 8(6), 559-562. https://doi.org/10.1093/jpids/piy126

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title = "Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days",

abstract = "In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0\%] [95\% confidence interval, 96.5\%-100.0\%]) but low specificity (66 of 4171 [1.6\%] [95\% confidence interval, 1.3\%-2.0\%]) and therefore should not be applied clinically to infants in this age group.",

keywords = "bacterial meningitis score, infants, sensitivity, specificity",

author = "Rees, \{Chris A.\} and Cruz, \{Andrea T.\} and Freedman, \{Stephen B.\} and Prashant Mahajan and Uspal, \{Neil G.\} and Pamela Okada and Aronson, \{Paul L.\} and Thompson, \{Amy D.\} and Ishimine, \{Paul T.\} and Schmidt, \{Suzanne M.\} and Nathan Kuppermann and Nigrovic, \{Lise E.\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Author(s) 2018. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved.",

year = "2019",

month = dec,

day = "1",

doi = "10.1093/jpids/piy126",

language = "English",

volume = "8",

pages = "559--562",

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T1 - Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

AU - Rees, Chris A.

AU - Cruz, Andrea T.

AU - Freedman, Stephen B.

AU - Mahajan, Prashant

AU - Uspal, Neil G.

AU - Okada, Pamela

AU - Aronson, Paul L.

AU - Thompson, Amy D.

AU - Ishimine, Paul T.

AU - Schmidt, Suzanne M.

AU - Kuppermann, Nathan

AU - Nigrovic, Lise E.

PY - 2019/12/1

Y1 - 2019/12/1

N2 - In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.

AB - In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.

KW - bacterial meningitis score

KW - infants

KW - sensitivity

KW - specificity

UR - https://www.scopus.com/pages/publications/85077263879

U2 - 10.1093/jpids/piy126

DO - 10.1093/jpids/piy126

M3 - Article

C2 - 30535235

AN - SCOPUS:85077263879

SN - 2048-7193

VL - 8

SP - 559

EP - 562

JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

IS - 6

ER -

Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Abstract

Keywords

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