Comparing Antibiotics and Surgery to Treat Appendicitis in Children

Peter Minneci; Erinn M. Hade; Jacqueline M. Saito; Grace Z. Mak; Ronald B. Hirschl; Samir Gadepalli; Michael A. Helmrath; Charles M. Leys; Thomas T. Sato; Dave R. Lal; Matthew P. Landman; Rashmi Kabre; Mary E. Fallat; Jennifer N. Cooper; Katherine J. Deans

doi:10.25302/05.21.CER.150731325

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

Peter Minneci
, Erinn M. Hade
, Jacqueline M. Saito
, Grace Z. Mak
, Ronald B. Hirschl
, Samir Gadepalli
, Michael A. Helmrath
, Charles M. Leys
, Thomas T. Sato
, Dave R. Lal
, Matthew P. Landman
, Rashmi Kabre
, Mary E. Fallat
, Jennifer N. Cooper
, Katherine J. Deans

Research output: Book/Report › Commissioned report › peer-review

Abstract

Background: Although curative, appendectomy is a major intra-abdominal operation with
associated perioperative risks, pain, and disability. A nonoperative management strategy with
antibiotics alone has the potential to treat the disease effectively with less negative impact on
the child and the family.
Objectives: To determine the effectiveness of nonoperative management by characterizing its
success rate and comparing treatment-related disability, health-related quality of life (HRQOL),
health care satisfaction, and treatment-associated complications of nonoperative management
vs surgery in children with uncomplicated appendicitis.

Original language	English
Publisher	Patient-Centered Outcomes Research Institute
Number of pages	121
DOIs	https://doi.org/10.25302/05.21.CER.150731325
State	Published - 11 May 2021

Access to Document

10.25302/05.21.CER.150731325

https://www.pcori.org/sites/default/files/Minneci352-Final-Research-Report.pdfLicense: Unspecified

Cite this

Minneci, P., Hade, E. M., Saito, J. M., Mak, G. Z., Hirschl, R. B., Gadepalli, S., Helmrath, M. A., Leys, C. M., Sato, T. T., Lal, D. R., Landman, M. P., Kabre, R., Fallat, M. E., Cooper, J. N., & Deans, K. J. (2021). Comparing Antibiotics and Surgery to Treat Appendicitis in Children. Patient-Centered Outcomes Research Institute. https://doi.org/10.25302/05.21.CER.150731325

@book{d6739a0e806c411cabc8bb3ae9cf4a61,

title = "Comparing Antibiotics and Surgery to Treat Appendicitis in Children",

abstract = "Background: Although curative, appendectomy is a major intra-abdominal operation with associated perioperative risks, pain, and disability. A nonoperative management strategy with antibiotics alone has the potential to treat the disease effectively with less negative impact on the child and the family. Objectives: To determine the effectiveness of nonoperative management by characterizing its success rate and comparing treatment-related disability, health-related quality of life (HRQOL), health care satisfaction, and treatment-associated complications of nonoperative management vs surgery in children with uncomplicated appendicitis.",

author = "Peter Minneci and Hade, \{Erinn M.\} and Saito, \{Jacqueline M.\} and Mak, \{Grace Z.\} and Hirschl, \{Ronald B.\} and Samir Gadepalli and Helmrath, \{Michael A.\} and Leys, \{Charles M.\} and Sato, \{Thomas T.\} and Lal, \{Dave R.\} and Landman, \{Matthew P.\} and Rashmi Kabre and Fallat, \{Mary E.\} and Cooper, \{Jennifer N.\} and Deans, \{Katherine J.\}",

year = "2021",

month = may,

day = "11",

doi = "10.25302/05.21.CER.150731325",

language = "English",

publisher = "Patient-Centered Outcomes Research Institute",

address = "United States",

}

TY - BOOK

T1 - Comparing Antibiotics and Surgery to Treat Appendicitis in Children

AU - Minneci, Peter

AU - Hade, Erinn M.

AU - Saito, Jacqueline M.

AU - Mak, Grace Z.

AU - Hirschl, Ronald B.

AU - Gadepalli, Samir

AU - Helmrath, Michael A.

AU - Leys, Charles M.

AU - Sato, Thomas T.

AU - Lal, Dave R.

AU - Landman, Matthew P.

AU - Kabre, Rashmi

AU - Fallat, Mary E.

AU - Cooper, Jennifer N.

AU - Deans, Katherine J.

PY - 2021/5/11

Y1 - 2021/5/11

N2 - Background: Although curative, appendectomy is a major intra-abdominal operation with associated perioperative risks, pain, and disability. A nonoperative management strategy with antibiotics alone has the potential to treat the disease effectively with less negative impact on the child and the family. Objectives: To determine the effectiveness of nonoperative management by characterizing its success rate and comparing treatment-related disability, health-related quality of life (HRQOL), health care satisfaction, and treatment-associated complications of nonoperative management vs surgery in children with uncomplicated appendicitis.

AB - Background: Although curative, appendectomy is a major intra-abdominal operation with associated perioperative risks, pain, and disability. A nonoperative management strategy with antibiotics alone has the potential to treat the disease effectively with less negative impact on the child and the family. Objectives: To determine the effectiveness of nonoperative management by characterizing its success rate and comparing treatment-related disability, health-related quality of life (HRQOL), health care satisfaction, and treatment-associated complications of nonoperative management vs surgery in children with uncomplicated appendicitis.

U2 - 10.25302/05.21.CER.150731325

DO - 10.25302/05.21.CER.150731325

M3 - Commissioned report

BT - Comparing Antibiotics and Surgery to Treat Appendicitis in Children

PB - Patient-Centered Outcomes Research Institute

ER -

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

Abstract

Access to Document

Fingerprint

Cite this