Effect of the procalcitonin assay on antibiotic use in critically ill children

Rachael K. Ross; Luke Keele; Sherri Kubis; Andrew J. Lautz; Adam C. Dziorny; Adam R. Denson; Kathleen A. O’Connor; Marianne R. Chilutti; Scott L. Weiss; Jeffrey S. Gerber

doi:10.1093/jpids/piy004

Effect of the procalcitonin assay on antibiotic use in critically ill children

Rachael K. Ross
, Luke Keele
, Sherri Kubis
, Andrew J. Lautz
, Adam C. Dziorny
, Adam R. Denson
, Kathleen A. O’Connor
, Marianne R. Chilutti
, Scott L. Weiss
, Jeffrey S. Gerber

University of Pennsylvania
Georgetown University
The Children's Hospital of Philadelphia
Cincinnati Children's Hospital Medical Center

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We retrospectively studied the effect of introducing procalcitonin into clinical practice on antibiotic use within a large academic pediatric intensive care unit. In the absence of a standardized algorithm, availability of the procalcitonin assay did not reduce the frequency of antibiotic initiations or the continuation of antibiotics for greater than 72 hours.

Original language	English
Pages (from-to)	E43-E46
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	7
Issue number	2
DOIs	https://doi.org/10.1093/jpids/piy004
State	Published - 15 May 2018
Externally published	Yes

Keywords

Antibiotics
Critical care
Pediatric
Procalcitonin

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10.1093/jpids/piy004

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title = "Effect of the procalcitonin assay on antibiotic use in critically ill children",

abstract = "We retrospectively studied the effect of introducing procalcitonin into clinical practice on antibiotic use within a large academic pediatric intensive care unit. In the absence of a standardized algorithm, availability of the procalcitonin assay did not reduce the frequency of antibiotic initiations or the continuation of antibiotics for greater than 72 hours.",

keywords = "Antibiotics, Critical care, Pediatric, Procalcitonin",

author = "Ross, \{Rachael K.\} and Luke Keele and Sherri Kubis and Lautz, \{Andrew J.\} and Dziorny, \{Adam C.\} and Denson, \{Adam R.\} and O{\textquoteright}Connor, \{Kathleen A.\} and Chilutti, \{Marianne R.\} and Weiss, \{Scott L.\} and Gerber, \{Jeffrey S.\}",

year = "2018",

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doi = "10.1093/jpids/piy004",

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T1 - Effect of the procalcitonin assay on antibiotic use in critically ill children

AU - Ross, Rachael K.

AU - Keele, Luke

AU - Kubis, Sherri

AU - Lautz, Andrew J.

AU - Dziorny, Adam C.

AU - Denson, Adam R.

AU - O’Connor, Kathleen A.

AU - Chilutti, Marianne R.

AU - Weiss, Scott L.

AU - Gerber, Jeffrey S.

PY - 2018/5/15

Y1 - 2018/5/15

N2 - We retrospectively studied the effect of introducing procalcitonin into clinical practice on antibiotic use within a large academic pediatric intensive care unit. In the absence of a standardized algorithm, availability of the procalcitonin assay did not reduce the frequency of antibiotic initiations or the continuation of antibiotics for greater than 72 hours.

AB - We retrospectively studied the effect of introducing procalcitonin into clinical practice on antibiotic use within a large academic pediatric intensive care unit. In the absence of a standardized algorithm, availability of the procalcitonin assay did not reduce the frequency of antibiotic initiations or the continuation of antibiotics for greater than 72 hours.

KW - Antibiotics

KW - Critical care

KW - Pediatric

KW - Procalcitonin

UR - https://www.scopus.com/pages/publications/85049860421

U2 - 10.1093/jpids/piy004

DO - 10.1093/jpids/piy004

M3 - Article

C2 - 29529219

AN - SCOPUS:85049860421

SN - 2048-7193

VL - 7

SP - E43-E46

JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

IS - 2

ER -

Effect of the procalcitonin assay on antibiotic use in critically ill children

Abstract

Keywords

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