Gastric pepsin in middle ear fluid of children with otitis media: clinical implications.

Zhaoping He; Robert C. O'Reilly; Devendra Mehta

doi:10.1007/s11882-008-0094-7

Gastric pepsin in middle ear fluid of children with otitis media: clinical implications.

Zhaoping He
, Robert C. O'Reilly
, Devendra Mehta

Alfred I. duPont Hospital for Children

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.

Original language	English
Pages (from-to)	513-518
Number of pages	6
Journal	Current Allergy and Asthma Reports
Volume	8
Issue number	6
DOIs	https://doi.org/10.1007/s11882-008-0094-7
State	Published - Nov 2008
Externally published	Yes

Access to Document

10.1007/s11882-008-0094-7

Cite this

@article{651ac00662b74193af55f4cc16a9cd07,

title = "Gastric pepsin in middle ear fluid of children with otitis media: clinical implications.",

abstract = "Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.",

author = "Zhaoping He and O'Reilly, \{Robert C.\} and Devendra Mehta",

year = "2008",

month = nov,

doi = "10.1007/s11882-008-0094-7",

language = "English",

volume = "8",

pages = "513--518",

journal = "Current Allergy and Asthma Reports",

issn = "1529-7322",

publisher = "Springer",

number = "6",

}

TY - JOUR

T1 - Gastric pepsin in middle ear fluid of children with otitis media

T2 - clinical implications.

AU - He, Zhaoping

AU - O'Reilly, Robert C.

AU - Mehta, Devendra

PY - 2008/11

Y1 - 2008/11

N2 - Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.

AB - Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.

UR - https://www.scopus.com/pages/publications/58149252541

U2 - 10.1007/s11882-008-0094-7

DO - 10.1007/s11882-008-0094-7

M3 - Review article

C2 - 18940143

AN - SCOPUS:58149252541

SN - 1529-7322

VL - 8

SP - 513

EP - 518

JO - Current Allergy and Asthma Reports

JF - Current Allergy and Asthma Reports

IS - 6

ER -

Gastric pepsin in middle ear fluid of children with otitis media: clinical implications.

Abstract

Access to Document

Other files and links

Fingerprint

Cite this