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Isolated pancreatic amylase deficiency: Probable error in maturation

  • Devendra I. Mehta
  • , Hugh H. Wang
  • , Robert E. Akins
  • , Lisa Wang
  • , Roy Proujansky
  • Alfred I. duPont Hospital for Children

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A boy with failure to thrive and isolated pancreatic amylase deficiency is described. Immunoprecipitation confirmed only salivary isoamylase in duodenal fluid at ages 20 and 33 months. Because normal pancreatic amylase messenger RNA was detected by reverse-transcriptase polymerase chain reaction in the fluid, failure of the normal maturation of pancreatic amylase secretion may explain the deficiency.

Original languageEnglish
Pages (from-to)844-846
Number of pages3
JournalJournal of Pediatrics
Volume136
Issue number6
DOIs
StatePublished - 2000

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