Pediatric Catatonia

Meghan Starner; Maxine Ames; Alexander J. Gordon; Mary Lynn Dell; Elora Hilmas; Josephine Elia

doi:10.1016/B978-0-323-51147-6.00013-2

Pediatric Catatonia

Meghan Starner
, Maxine Ames
, Alexander J. Gordon
, Mary Lynn Dell
, Elora Hilmas
, Josephine Elia

Thomas Jefferson University
St. John's University
Ohio State University
Alfred I. duPont Hospital for Children

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Pediatric catatonia is a syndrome with characteristic features, involving motor, speech, behavior, and autonomic dysregulation. It is usually associated with various medical, neurologic, and neuropsychiatric disorders, as well as medication toxicity or withdrawal. Imbalances in glutamatergic function, resulting in decreased γ-aminobutyric acid A (GABAA) function, are one of the mechanisms supported by pharmacologic and imaging studies. Benzodiazepines enhance the effects of GABAA and are the first-line treatments in effectively treating catatonia in children and adults. Catatonia has significant morbidity and mortality; however, it often is unrecognized, especially in pediatric medical and psychiatric settings.

Original language	English
Title of host publication	Complex Disorders in Pediatric Psychiatry
Subtitle of host publication	A Clinician's Guide
Publisher	Elsevier
Pages	155-167
Number of pages	13
ISBN (Electronic)	9780323511476
ISBN (Print)	9780323511728
DOIs	https://doi.org/10.1016/B978-0-323-51147-6.00013-2
State	Published - 1 Jan 2018
Externally published	Yes

Keywords

Benzodiazepines
Catatonia
Dysautonomia
ECT
GABA
Glutamatergic

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10.1016/B978-0-323-51147-6.00013-2

Cite this

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abstract = "Pediatric catatonia is a syndrome with characteristic features, involving motor, speech, behavior, and autonomic dysregulation. It is usually associated with various medical, neurologic, and neuropsychiatric disorders, as well as medication toxicity or withdrawal. Imbalances in glutamatergic function, resulting in decreased γ-aminobutyric acid A (GABAA) function, are one of the mechanisms supported by pharmacologic and imaging studies. Benzodiazepines enhance the effects of GABAA and are the first-line treatments in effectively treating catatonia in children and adults. Catatonia has significant morbidity and mortality; however, it often is unrecognized, especially in pediatric medical and psychiatric settings.",

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T1 - Pediatric Catatonia

AU - Starner, Meghan

AU - Ames, Maxine

AU - Gordon, Alexander J.

AU - Dell, Mary Lynn

AU - Hilmas, Elora

AU - Elia, Josephine

PY - 2018/1/1

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N2 - Pediatric catatonia is a syndrome with characteristic features, involving motor, speech, behavior, and autonomic dysregulation. It is usually associated with various medical, neurologic, and neuropsychiatric disorders, as well as medication toxicity or withdrawal. Imbalances in glutamatergic function, resulting in decreased γ-aminobutyric acid A (GABAA) function, are one of the mechanisms supported by pharmacologic and imaging studies. Benzodiazepines enhance the effects of GABAA and are the first-line treatments in effectively treating catatonia in children and adults. Catatonia has significant morbidity and mortality; however, it often is unrecognized, especially in pediatric medical and psychiatric settings.

AB - Pediatric catatonia is a syndrome with characteristic features, involving motor, speech, behavior, and autonomic dysregulation. It is usually associated with various medical, neurologic, and neuropsychiatric disorders, as well as medication toxicity or withdrawal. Imbalances in glutamatergic function, resulting in decreased γ-aminobutyric acid A (GABAA) function, are one of the mechanisms supported by pharmacologic and imaging studies. Benzodiazepines enhance the effects of GABAA and are the first-line treatments in effectively treating catatonia in children and adults. Catatonia has significant morbidity and mortality; however, it often is unrecognized, especially in pediatric medical and psychiatric settings.

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KW - Catatonia

KW - Dysautonomia

KW - ECT

KW - GABA

KW - Glutamatergic

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DO - 10.1016/B978-0-323-51147-6.00013-2

M3 - Chapter

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SN - 9780323511728

SP - 155

EP - 167

BT - Complex Disorders in Pediatric Psychiatry

PB - Elsevier

ER -

Pediatric Catatonia

Abstract

Keywords

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