Predictors of crisis management in genetic generalized epilepsies in a Colombian cohort, a purpose beyond clinical variables

Objective: Identify factors predictors with crisis management in patients with generalized genetic epilepsies. Patients and methods: Case-control study with a cohort of patients greater than 14 years old diagnosed with generalized genetic epilepsy, and 12-month follow-up, excluded patients with a diagnosis of epileptic encephalopathy. Sociodemographic, clinical characteristics and survey characteristics were evaluated for the evaluation of relapse factors; bivariate and multivariate analyzes were performed using binary logistic regression. Results: Between November 2014 and December 2016, 250 patients who met the selection criteria were evaluated. The factors predictors with epileptic seizure control were: rmedical comorbidities (OR: 7.33, 95% CI: 2.89-18.57, P<.001), health plan assurance (OR: 3.61, 95% CI: 1.40- 9.26, P.008), individual attitudes (OR: 3.82, 95% CI: 2.08-7.00, P<.001) and the number of seizures on admission to the epilepsy program (OR: 0.95, 95% CI 0.92-0.98, P.007); There was no association with a psychiatric, family or psychoactive substance use history. Conclusion: It is demonstrated that 30% of the crisis control of this cohort of patients can be explained by the factors found, so that if they are impacted and a comprehensive intervention is performed, there is a direct impact on crisis control and thus in the long-term forecast.