Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development

Takeshi Tsuda; Te Cheng Pan; Lucia Evangelisti; Mon Li Chu

doi:10.1002/ar.a.10002

Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development

Takeshi Tsuda
, Te Cheng Pan
, Lucia Evangelisti
, Mon Li Chu

Thomas Jefferson University

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (Ell) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium.

Original language	English
Pages (from-to)	93-96
Number of pages	4
Journal	Anatomical Record
Volume	270
Issue number	2
DOIs	https://doi.org/10.1002/ar.a.10002
State	Published - 1 Feb 2003
Externally published	Yes

Keywords

Aorta
Differential display
Extracellular matrix
Heart development

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10.1002/ar.a.10002

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title = "Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development",

abstract = "By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (Ell) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium.",

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author = "Takeshi Tsuda and Pan, \{Te Cheng\} and Lucia Evangelisti and Chu, \{Mon Li\}",

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T1 - Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development

AU - Tsuda, Takeshi

AU - Pan, Te Cheng

AU - Evangelisti, Lucia

AU - Chu, Mon Li

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Y1 - 2003/2/1

N2 - By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (Ell) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium.

AB - By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (Ell) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium.

KW - Aorta

KW - Differential display

KW - Extracellular matrix

KW - Heart development

UR - https://www.scopus.com/pages/publications/0141959307

U2 - 10.1002/ar.a.10002

DO - 10.1002/ar.a.10002

M3 - Article

C2 - 12524683

AN - SCOPUS:0141959307

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VL - 270

SP - 93

EP - 96

JO - Anatomical Record

JF - Anatomical Record

IS - 2

ER -

Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development

Abstract

Keywords

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