The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease

Sachin S. Pawar; Julie A. Panepinto; David C. Brousseau

doi:10.1002/pbc.20872

The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease

Sachin S. Pawar
, Julie A. Panepinto
, David C. Brousseau

Medical College of Wisconsin

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Exhaled nitric oxide (FE_NO) has been shown to be decreased in children with sickle cell disease. We sought to evaluate the effect of sickle cell vaso-occlusive crisis (VOC) on FE_NO levels. We measured FE _NO levels in 42 children with sickle cell disease, 29 in their baseline health and 13 during an acute VOC. There was no difference in FE _NO levels between children at baseline (15.12 ± 9.32 ppb) and those during an acute VOC (15.68 ± 7.26 ppb; P = 0.794). FE_NO is not a useful marker of acute VOC in children with sickle cell disease.

Original language	English
Pages (from-to)	111-113
Number of pages	3
Journal	Pediatric Blood and Cancer
Volume	50
Issue number	1
DOIs	https://doi.org/10.1002/pbc.20872
State	Published - Jan 2008
Externally published	Yes

Keywords

Exhaled nitric oxide
Sickle cell anemia

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10.1002/pbc.20872

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title = "The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease",

abstract = "Exhaled nitric oxide (FENO) has been shown to be decreased in children with sickle cell disease. We sought to evaluate the effect of sickle cell vaso-occlusive crisis (VOC) on FENO levels. We measured FE NO levels in 42 children with sickle cell disease, 29 in their baseline health and 13 during an acute VOC. There was no difference in FE NO levels between children at baseline (15.12 ± 9.32 ppb) and those during an acute VOC (15.68 ± 7.26 ppb; P = 0.794). FENO is not a useful marker of acute VOC in children with sickle cell disease.",

keywords = "Exhaled nitric oxide, Sickle cell anemia",

author = "Pawar, \{Sachin S.\} and Panepinto, \{Julie A.\} and Brousseau, \{David C.\}",

year = "2008",

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doi = "10.1002/pbc.20872",

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journal = "Pediatric Blood and Cancer",

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T1 - The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease

AU - Pawar, Sachin S.

AU - Panepinto, Julie A.

AU - Brousseau, David C.

PY - 2008/1

Y1 - 2008/1

N2 - Exhaled nitric oxide (FENO) has been shown to be decreased in children with sickle cell disease. We sought to evaluate the effect of sickle cell vaso-occlusive crisis (VOC) on FENO levels. We measured FE NO levels in 42 children with sickle cell disease, 29 in their baseline health and 13 during an acute VOC. There was no difference in FE NO levels between children at baseline (15.12 ± 9.32 ppb) and those during an acute VOC (15.68 ± 7.26 ppb; P = 0.794). FENO is not a useful marker of acute VOC in children with sickle cell disease.

AB - Exhaled nitric oxide (FENO) has been shown to be decreased in children with sickle cell disease. We sought to evaluate the effect of sickle cell vaso-occlusive crisis (VOC) on FENO levels. We measured FE NO levels in 42 children with sickle cell disease, 29 in their baseline health and 13 during an acute VOC. There was no difference in FE NO levels between children at baseline (15.12 ± 9.32 ppb) and those during an acute VOC (15.68 ± 7.26 ppb; P = 0.794). FENO is not a useful marker of acute VOC in children with sickle cell disease.

KW - Exhaled nitric oxide

KW - Sickle cell anemia

UR - https://www.scopus.com/pages/publications/36849095988

U2 - 10.1002/pbc.20872

DO - 10.1002/pbc.20872

M3 - Article

C2 - 16619223

AN - SCOPUS:36849095988

SN - 1545-5009

VL - 50

SP - 111

EP - 113

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 1

ER -

The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease

Abstract

Keywords

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