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The Society of Thoracic Surgeons/World Society for Pediatric and Congenital Heart Surgery/European Congenital Heart Surgeons Association 2026 Clinical Practice Guidelines on Indications and Timing of Pulmonary Valve Replacement in Repaired Tetralogy of Fallot

  • Jennifer S. Nelson
  • , Jimmy C. Lu
  • , Awais Ashfaq
  • , Michael H. Kwon
  • , Anna Kamp
  • , Elizabeth Stephens
  • , Mitchell I. Cohen
  • , Camilla Rossi
  • , Pallavi Sood
  • , Nestor Sandoval
  • , Vladimiro Vida
  • , Cheul Lee
  • , Amber D. Khanna
  • , Castigliano Bhamidipati
  • , Attilio Lotto
  • , Jeffrey D. Zampi
  • , Eleftherios Protopapas
  • , Anastasios C. Polimenakos
  • , Susana Cruz Beltran
  • , Yishay Orr
  • Danial Ahmad, Christo Tchervenkov, George Sarris, Jeffrey P. Jacobs, James D. St. Louis
  • Nemours Children's Health System
  • University of Central Florida
  • University of Michigan, Ann Arbor
  • Cincinnati Children's Hospital Medical Center
  • Boston Children's Hospital
  • Nationwide Children’s Hospital
  • Mayo Clinic Rochester, MN
  • Inova Children's Hospital
  • Weill Cornell Medical Center
  • The Society of Thoracic Surgeons
  • Fundación Cardioinfantil - Instituto de Cardiología
  • University of Padua
  • The Catholic University of Korea
  • Canberra Hospital
  • Royal Prince Alfred Hospital
  • Oregon Health and Science University
  • Alder Hey Children's NHS Foundation Trust
  • Aghia Sophia Children's Hospital
  • Augusta University
  • University of Florida
  • Baylor College of Medicine
  • University of Pittsburgh
  • McGill University
  • Athens Heart Surgery Institute

Research output: Contribution to journalArticlepeer-review

Abstract

The Society of Thoracic Surgeons/World Society for Pediatric and Congenital Heart Surgery/European Congenital Heart Surgeons Association 2026 Clinical Practice Guidelines on Indications and Timing of Pulmonary Valve Replacement in Repaired Tetralogy of Fallot incorporate the most recent evidence for pulmonary valve replacement in this growing population. New evidence related to advanced imaging, electrophysiology testing, exercise testing, and transcatheter pulmonary valve replacement has emerged in the last 5 years. Compared with existing guidelines, the current update places emphasis on symptoms (children and adults), ventricular volumes (adults), and the need for invasive electrophysiology study before replacing the pulmonary valve (adults). This document is Part 1 and is accompanied by 2 other multisociety documents: Part 2: Society of Thoracic Surgeons/World Society for Pediatric and Congenital Heart Surgery/European Congenital Heart Surgeons Association 2026 Expert Consensus Document on Timing, Indications, and Options for Pulmonary Valve Replacement in Children with Repaired Tetralogy of Fallot, and Part 3: Society of Thoracic Surgeons/World Society for Pediatric and Congenital Heart Surgery/European Congenital Heart Surgeons Association 2026 Expert Opinion on the Role of Exercise Testing in Determining Optimal Timing of Pulmonary Valve Replacement in Tetralogy of Fallot. With this 3-part series, multidisciplinary team assessment, treatment planning, and long-term surveillance are also reinforced.

Original languageEnglish
JournalAnnals of Thoracic Surgery
Early online date22 Apr 2026
DOIs
StateE-pub ahead of print - 22 Apr 2026

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