Genetic Abnormalities and Congenital Malformations as a Cause of Cerebral Palsy

Recent evidence suggests that genetics may play a prominent role in the development of cerebral palsy. Genetics has different avenues by which it may contribute to disease. Several studies have examined how a known risk factor along with a genetic predisposition may lead to cerebral palsy. Others have studied how singlegene changes and deletions or duplications of genetic material are likely involved in the pathogenesis of disease. Finding a genetic cause may aid in treatment, prognostication, and family planning. Thus, in consultation with a geneticist, it is important to consider a genetic evaluation in patients with cerebral palsy.