Neurourologic consequences of accidental intrathecal vincristine: A case report

Inadvertent intrathecal administration of vincristine results in severe neurotoxicity. Motor and sensory bladder dysfunction have been reported but the long‐term urologic consequences are unknown due to the associated high mortality. We report a case of accidental intrathecal vincristine administration with patient survival and follow‐up of 24 months. The child developed a lower motor neuron neuropathic bladder requiring intermittent self‐catheterization of the bladder. Urinary tract management of these children should be based on the urodynamic findings. © 1995 Wiley‐Liss, Inc.